Presentations

2024

Antibody-Drug Conjugates
Min Sun (Esther) Kang
Radical Cyclizations in Total Synthesis via Photoredox Catalysis
William Zhao
High Throughput Screening Strategies in Drug Discovery
Zihan (Blair) Dong
Dearomatization Strategies
Qinyan (Anna) Cai
Conotoxins: therapeutic potentials and applications from the sea
Dr. Danielle Morgan
Polypharmacology: A Brief History of Drug Design Philosophy
Sean Huth
Photon Upconversion
Katherine Burton
Multiple Myeloma
Philip Raftopoulos
The Adaptive Immune System: Function, Vaccination, and Disease
Zane Boyer
Where’s the Fun in Fungus? An Introduction to the Antifungal Space
Iona McWhinnie
Frustrated Lewis Acid-Base Pair
Jingjia (Alina) Chen
Cellular Stress Response
Chun (Alice) Li
Nucleoside Therapies: Mechanism of Action, Development, SAR, and Synthesis
Noah Bissonnette

2023

HIV/AIDS
Alice Long
Clusters: an introduction through case studies
Ruizhe (Jerry) Chen
ALS: the fall to the frozen
Roderick (Chenmengxiao) Pan
Aging: the mechanisms of getting old and the race for immortality
Dr. Steve Knutson
Optogenetics: control nature with light
Dr. Steve Knutson
Total Synthesis of Hyperforin: A Quest of Synthetic Efficiency
Dr. Jiaxin (Jay) Xie
Nuclear Medicine – From Physics to Diagnostic and Therapeutic Principles
Dr. Alexander Haseloer
The Ubiquitin Code
Dr. Benito Buksh
Enamine
William Lyon
Molecular Editing
William Carson
Ligand-coupling on hypervalent species: Transition metal chemistry without the metal
Dr. Benjamin Boyle
The Chemistry of Eyesight
Katherine Burton
Electrocatalysis
Dr. Colin Gould
Visible Light Induced Single Electron Transfer via EDA Complexes
Noah Bissonnette
Circadian Rhythm: Molecular Mechanisms and Pharmacology
Scott Pedersen

2022

Human Dose Projections in Drug Discovery
Dr. Nick Intermaggio
Gut Microbiota: our inner ecosystem
Roderick (Chenmengxiao) Pan
The Past, Present, and Future of Genetic Engineering
Dr. Steve Knutson
Bacterial Anticancer Therapy
Sean Huth
Transition-Metal Hydride HAT: Radical Hydrofunctionalization of Olefins
Dr. Amy Chan
Metal-Metal Bonds in Organic Catalysis
Dr. Artem Tsymbal
Induced Pluripotent Stem Cells (iPSCs)
Dr. James Oakley
Pain
Edna Mao
Iron Porphyrins as Catalysts for Carbene-Based Synthetic Transformations
Dr. Nate Dow
Dynamic covalent chemistry: Simple reactions for complex systems
Dr. Benjamin Boyle
Genetic Code Expansion
Dr. Benito Buksh
The Development of Radical-Based Palladium Chemistry
Andria Pace
Forensic Chemistry: Forensic Science from a Chemist’s Perspective
Andria Pace
Rheumatoid Arthritis and Citrullinated Proteins
Jingjia (Alina) Chen
Qubits and Quantum Coupling
Dr. Colin Gould
Introduction to Gene Therapy and AAV Therapeutics
Noah Bissonnette
Mechanistic Aspects of Nitrogen-Ligated Nickel(I) Intermediates
Dr. Cesar Nicolas Prieto Kullmer

2021

Gut Microbiota in Human Metabolic Health and Disease
Dr. Olivia Garry
On the Relationship of α–synuclein and Parkinson’s Disease
Dr. Nick Intermaggio
Oncogenes and the “Death Star” of Cancer
Sean Huth
Siderophores: Ligands of Life
Dr. Grant Edwards
Targeting Cell Cycle Proteins for Cancer Therapeutics
Dr. Holt Sakai
Phenyl Bioisosterism – A Solved Challenge?
Dr. Michael Heilmann
Drug Metabolism and Toxicity
Edna Mao
Human consciousness
Dr. Beryl Li
Non-Classical Carbocations
Dr. Nate Dow
Molecular Glues
Dr. Ciaran Seath
Radical Chemistry of tert-Butoxide
Dr. Christian Oswood
Formation and Reactivity of N–Centered Radicals
Dr. Amy Chan
Super-resolution Microscopy
Dr. James Oakley
Protein Misfolding and Degenerative Diseases
Dr. Aaron Trowbridge
Migratory Functional-Group Modification
Dr. Yufan Liang

2020

Metal-alkyl complexes of iron and cobalt porphyrins: photonic and non-photonic chemistry
Dr. Marissa Lavagnino
CAR T cell Therapy
Dr. Gabby Lovett
Immuno-Oncology: Targeting STING
Dr. Johannes Diesel
Conformational Effects of Fully Substituted Carbons
Dr. Nick Intermaggio
Plasmonic Gold Nanoparticles as Theranostic Agents
Dr. Agustin Millet
Recent Developments of Cobalt-Catalyzed Hydrofunctionalization of Olefins
Dr. Yufan Liang
Liquid–Liquid Phase Separation in Biology
Dr. Benito Buksh
Inverted Ligand Fields
Dr. Cesar Nicolas Prieto Kullmer
Catalysis by Small Peptides
Dr. Mario Wiesenfeldt
Nuclear Structure and Isomerism
Dr. Ian Perry
Pharmaceutical Development for Rare & Neglected Diseases
Dr. Robert Pipal
Epigenetics and Aging
Dr. Olivia Garry
Antibodies and their Therapeutic Applications
Dr. Nick Till
An Introduction to Mass-Spectrometry-Based Proteomics
Dr. Nick Till
Pesticides in Agrochemical Research and Development
Dr. Robert Pipal
Fragment-Based Drug Discovery & Activity-Based Protein Profiling
Dr. Junyong Kim
Introduction to Computational Chemistry
Dr. Lorenzo Bizzini
Bismuth Catalysis for Organic Synthesis
Dr. Xiaheng Zhang
Radical Cage Effects
Dr. Patrick Sarver
Atropisomers
Dr. Nate Dow
Physics, Chemistry, and Biology in Art Conservation
Dr. Daniela Arias-Rotondo
Anesthesia
Dr. Christian Oswood
Atmospheric Chemistry: The Many Roles of Ozone in the Stratosphere and Troposphere
Dr. Marissa Lavagnino
Food, Food Chemistry, and the Gustatory Sense
Dr. Maria González Esguevillas
Chemical Game Theory
Dr. Jacob Kautzky
Artificial Photosynthesis: A Synthetic Organic Perspective
Dr. Wei Liu
Macrocyclic Peptides
Dr. Vlad Bacauanu
Viral Entry
Dr. Daniel Kim

2019

Selective C-F bond Functionalization in Multifluoroarenes and Trifluoroarenes and Trifluoromethylarenes
Dr. Xiangbo Zhao
Carbenes: multiplicity and reactivity
Dr. Beryl Li
Total Syntheses Enabled by Cross Coupling
Dr. Xiaheng Zhang
Nonperfect Synchronization
Dr. Patrick Sarver
Halogen Bonding
Dr. Gabby Lovett
Bioisosteres of Common Functional Groups
Dr. Ian Perry
High Energy Materials
Dr. Vlad Bacauanu
PROteolysis Targeting Chimera (PROTAC) Targeted Intracellular Protein Degradation
Dr. Junyong Kim
The Olifactory System
Bioceramic Materials
Dr. Maria González Esguevillas
Metal-Organic Frameworks (MOFs)
Dr. Marissa Lavagnino
Boron Homologation
Dr. Zhe Dong
Decarboxylative and Decarbonylative Couplings of (Hetero)Aryl Carboxylic Acids and Derivatives
Dr. Yufan Liang
Proximity- and Affinity- Based Labeling Methods for Interactome Mapping
Dr. Beryl Li

2018

Chemistry of First-Row Transition Metal Photocatalysts
Switchable Catalysis
Dr. Tiffany Chen
Linear Free Energy Relationships
Dr. Nick Till
Machine Learning
Dr. Jacob Kautzky
Polyoxometalate Photocatalysis
Cobalt in Organic Synthesis
Metal Nanoparticles in Catalysis
Dr. Maria González Esguevillas
Ultrafast Spectroscopic Methods: Fundamental Principles and Applications in Photocatalysis
Dr. Nick Till
Quantum Dots: Applications in Electron and Energy Transfer Processes
Dr. Gabby Lovett
PET Imaging
Dr. Robert Pipal
Spin-Orbit Coupling and Inorganic Photocatalysts
Recent Advances in Cross-Coupling by Manganese Catalysis
Dr. Xiaheng Zhang
Recent Developments in Nucleophilic Fluorination
Dr. Vlad Bacauanu
Advances in Cancer Immunotherapy
Chemical Graph Theory
Dr. Jacob Kautzky
Smart Materials: Design and Applications

2017

Reductive Elimination from High-Valent Palladium
Dr. Kazunori Nagao
Synthesis and Applications of Fluorinated ⍺-Amino Acids
Central Nervous System Drug Design
Stefan McCarver
Phosphorescent OLEDs
Jeff Lipshultz
Novel Applications of Phosphorus in Catalysis for Organic Synthesis
Construction of C(sp3 )–N Bonds with Copper Catalysis
Dr. Yufan Liang
Photopharmacology
Dr. Dominik Koelmel
Photosynthesis – An Organic Chemist’s Guide
A Brief Survey on Synthesis and Catalytic Reactivity of Metal-Metal Bond Complexes
Chemistry and Biology of Hallucinogens
Jeff Lipshultz
Career of Erick Carreira
Dr. Simon Allmendinger
Complex Molecule Synthesis Enabled by Photochemistry
Dr. Joseph Badillo
Selectivity in Non-Directed C–H Functionalization of sp3 C–H Bonds
Dr. Megan Shaw
Flavins: A Bio-Inspired Approach to Photocatalysis
Frontiers in Solar Cells
Dr. Jian Jin

2016

Functionalization of C–O Bonds
Stefan McCarver
Strategies in Biomimetic Catalysis
Iron Catalyzed Cross-Coupling
Jack Terrett
New Click Reactions
In Silico Drug Discovery
Dr. Joseph Badillo
Structural Misassignment of Natural Products
Jeff Lipshultz
Transition Metal Mediated Fluorination of Arenes
Marcus Theory
Valerie Shurtleff
Deactivation Pathways in Transition Metal Catalysis
Stefan McCarver
Radical Enzymes
Dr. Jian Jin

2015

Noncanonical Nucleosides
Valerie Shurtleff
Catalytic Strategies for Biofuel Production
Jack Terrett
Protein-Engineered Biocatalysts in Industry
Stefan McCarver
The Magic Methyl Effect
Patricia Zhang
Antibody Drug Conjugates
Tracy Liu
Thiyl Radicals in Organic Synthesis
Dr. Jian Jin
Recent Advances in Selective Olefin Metathesis Reactions
Jeff Lipshultz
Behind the Scenes with Transition Metal Photocatalysts
Eric Welin

2014

Strategies in Synthetic Planning
Jennifer Alleva
Asymmetric Organocatalysis with N-Heterocyclic Carbenes
Dr. Adam Noble
Redox-Active Ligands in Catalysis
Andrew Capacci
Applications and Synthesis of Deuterium-Labeled Compounds
Chris Prier
On the Relationship Between Reactivity and Selectivity
Valerie Shurtleff
Classics in Pharmaceutical Process Chemistry
Jennifer Alleva

2013

Samarium(II) Iodide in Organic Synthesis
Dr. Aroop Chandra
Highlights from the Career of Jeffrey S. Moore
Chris Jamison
The Career of Harry B. Gray
Rob Comito
The Career of Kevan Shokat
Michael Pirnot
Nucleoside Derivatives as Drugs
Dr. Raphaëlle Berger
The Chemistry of Nine-Membered Enediyne Natural Products
Dr. Zhang Wang
Electrocyclizations and Torquoselectivity
Andrew Capacci
Mechanistic Studies in Copper Catalysis
Jennifer Alleva
Mechanistic Insights into Cross Coupling Reactions
Eric Welin
Career of Frances H. Arnold
Chris Prier
Metal-Organic Frameworks: Applications in Heterogeneous Catalysis
Jack Terrett
Quantifying Nucleophilicity and Electrophilicity: The Mayr Scales
Valerie Shurtleff
Benzyne: History, Generation, and Reactivity
Eric Welin
Radical Cyclizations in Total Synthesis
Patricia Zhang
Metal Organic Frameworks and Covalent Organic Frameworks
Rob Comito
The Chemistry of 1,2-diamines
Dr. Wei Li
Innovative Biotechnology Companies and their Academic Origins
Jack Terrett
The Chemistry of Frustrated Lewis Pairs
Tracy Liu

2012

Lies My Sophomore Organic Professor Told Me
Chris Jamison
The Future of Total Synthesis
Dr. Jason Stevens
Basic Biology of Viruses and Pharmaceutical Development of Antiviral Medications
Mark Vander Wal
Bioorthogonal Chemistry: History, State of the Art, and Applications
Michael Pirnot
The Chemistry of Cofactors: Thiamine, Biotin and Pyridoxal Phosphate
Andrew Capacci
Diabetes and Current Therapeutics
Scott Simonovich
Catalysis in Continuous Flow
Rob Comito
Five Drugs or Clinical Candidates Derived from Natural Products that are Produced by Total Synthesis
Jeff Garber
Highlights from Top Pre-Tenure Faculty
Jennifer Alleva
The Career of Gregory C. Fu
Eric Welin

2011

Physical Organic Photochemistry
Scott Simonovich
The Career of Makoto Fujita
Dr. Kai Xi
Catalytic Asymmetric Hydroaminations
Anna Allen
Recent Syntheses Published in Nature
Jeff Garber
Interaction of Organic Radicals with Transition Metals
Chris Prier
Chiral Olefins as Ligands for Asymmetric Catalysis
Hui-Wen Shih
Radical Cations: Generation, Reactivity, Stability
Anthony Casarez
Highlights from the Top Three Chinese Research Groups
Michael Pirnot
Coupling Chemistry of High Oxidation State Copper and Palladium
Rob Comito
Small Molecule Development: From Inception to Market
Anthony Casarez
Recent Advances in Directed Protein Evolution
Hui-Wen Shih
Bioconjugation: Chemical Approaches to Protein Modification
Chris Prier
Mechanistic Classes of Antibacterials
Benjamin Horning

2010

Pd in Buchwald-Hartwig C-N & C-O Couplings
Phong Pham
Metal Catalyzed Redox Reactions
Nathan Jui
Recent Developments in Rhodium Carbene and Nitrene Chemistry
Brian Laforteza
Career of Tom Muir
Scott Simonovich
C-H Bond Functionalization
Mark Vander Wal
Recent Developments in Homogeneous Gold Catalysis
David Nagib
Career of Dennis Dougherty: Ion Channels
Alex Warkentin
Six Most Innovative Total Syntheses
Anthony Casarez
Hydrogen Storage for Mobile Applications
Jeffrey Van Humbeck
Buchwald-Hartwig C-C Bond Formation
Dr. Andrew Dilger
Important Yet Forgotten Organic Transformations
Benjamin Horning
Career of Michael Krische
Hui-Wen Shih
Recent Developments in Cascade Catalysis
Spencer Jones
Important Mechanistic Studies
Jeffrey Van Humbeck
Polymetallic Asymmetric Catalysts
Brian Laforteza
Basics of Electron Transfer
Mark Vander Wal
Career of Benjamin Cravatt
Benjamin Horning
Syntheses Published in Science in the Last Decade
Chris Jamison

2009

Career of Stuart Schreiber
Benjamin Horning
Biological Applications of Organofluorine Compounds
Anna Allen
Career of Hisashi Yamamoto
Dr. Esther Lee
Cascades in Total Synthesis
Phong Pham
Comparative Total Syntheses of Strychnine
Nathan Jui
Total Syntheses of Manzamine A
Spencer Jones
Kinase Chemical Genetics
Alex Warkentin
Fundamentals of Computational Chemistry
The Alder-Ene Reaction
Anthony Casarez
Career of Samuel Danishefsky
Bryon Simmons
Career of Daniel Nocera
Jeffrey Van Humbeck
Nucleophilic Dearomatization
Dr. Mark Pickworth
Synthetic Approaches to Pyrroloindoline Natural Products
Joseph Carpenter
Anion Binding in Catalysis
Dr. Andrew McNally
RNAi and its Applications
Diane Carrera

2008

Directed Evolution of Enzymes
Dr. Sebastian Rendler
Anion Binding Organic Ligands
Dr. Hahn Kim
Transition Metal-catalysed Enantioselective Conjugate Additions
Dr. Allan Watson
Career of Carolyn Bertozzi
David Nagib
Lewis Base Catalysis
Anthony Mastracchio
High-Throughput Catalysis
Dr. Jay Conrad
Supramolecular Catalysis
Dr. Staffan Torssell
Phase Transfer Catalysis
Anthony Mastracchio
Enantioselective Lithiation
Spencer Jones
Enolate Formation and Reactivity
Frontier Orbital Interactions: Stereoselectivity
Phong Pham
Decarboxylative Cross-Coupling Chemistry
Nathan Jui
Photoinduced Electron Transfer: Strategies for Organic Synthesis
Alex Warkentin
Olefin Metathesis: catalysts excluding Schrock, Grubbs, & Hoveyda
Jeffrey Van Humbeck

2007

Microreactors and Microfluidic Cells in Organic Synthesis
Joseph Carpenter
Quantum Tunneling in Chemical Reactions
Diane Carrera
Conservation of Helical Asymmetry
Bryon Simmons
Biomimetic Chemistry
David Nagib

2006

The Mechanism of Lithium-Halogen Exchange
Sandra Lee
Asymmetric Hydrogen-Bond Catalysis
Anthony Mastracchio
Career of Christopher T. Walsh
Teresa Beeson
Conservation of Orbital Symmetry
Robert R. Knowles
Application of Kinetics to Organic Chemistry
Diane Carrera
Carbene Mediated C-H Activation
Joseph Carpenter

2005

Vicinal Quaternary Stereogenic Centers
Dr. Gerald Lelais
Asymmetric Nucleophilic Amine Bases
Dr. R. Ian Storer
Boron-Alkyl Suzuki Couplings
Nicole Goodwin
Aromatic Interactions
Robert R. Knowles
The Nature of the Hydrogen Bond
Jamison Tuttle
Modern Mass Spectrometry
Sandra Lee
Comparative Synthesis of Taxol
Ian Mangion
Comparative Synthesis of CP-Molecules
Jamison Tuttle
Synthesis of FR182877
Sandra Lee
Comparative Synthesis of Vancomycin
Ian Mangion
Molecular Imprinted Polymers
Diane Carrera
Kinetic Isotope Effect
Robert R. Knowles
Hypervalent Silicon
Dr. R. Ian Storer

2004

Heterocycles II
Joel Austin
Hantzsch Esters
Jamison Tuttle
The Intramolecular Heck Reaction
Robert R. Knowles
Catalytic Asymmetric Epoxidations
Teresa Beeson
General Methods for Enantioselective Cyclopropanations
Dr. Roxanne K. Kunz
Career of Robert H. Grubbs
Sean P. Brown
Enamines – Structure, Reactivity and Synthetic Applications
Ian Mangion
Discodermolide – A Synthetic Challenge
Nicole Goodwin
Catalytic Enantioselective Aziridinations
Sandra Lee
Catalyst Directed Asymmetric Hydrogenation of Carbonyls

2003

Heterocycles Part 1
Joel Austin
Potent Antimalarial Agent Artmisinin – Synthesis and Mode of Action
Dr. Ioana Drutu
Hyperconjugation
Alan B. Northrup
Transition Metal Catalyzed Non-Traditional Cycloadditions
Ian Mangion
N-Heterocyclic Carbenes
Nicole Goodwin
Cinchona Alkaloids in Asymmetric Catalysis
The Chemistry of Hypervalent Iodine
Sandra Lee
Mechanism and Application of Salen Ligands in Asymmetric Catalysis
Conformational Analysis of Medium Ring
Non-Linear Effects
Jake Wiener

2002

The Selective Aldol Reaction
Alan B. Northrup
Strained Silacycles
Christopher Borths
Dynamic Kinetic Resolutions
Jake Wiener
Career of K. Barry Sharpless
Nicole Goodwin
Buchwald-Hartwig Chemistry
Ian Mangion
Non-Metathesis Ruthenium-Catalyzed Rxn’s for Organic Synthesis
Tristan Lambert
Highlights of the Career of Robert R. Bergman
Vy Maria Dong

2001

Enantioselective Michael Additions in Natural Product Synthesis
Julie Park
Solid Phase Reagents
Catharine Larsen
Beta-Amino Acids
Sean P. Brown
Dynamic Combinatorial Chemistry
Nick A. Paras
Ligand Accelerated Lewis Acid Catalysis
Christopher Borths
Nickel-Catalyzed Cycloadditions
Tristan Lambert
Catalytic Enantoselective Additions to C=N
Tehshik P. Yoon
The Career of Peter Schultz
Nick A. Paras
Comparative Synthesis of Gelsemine
Joel Austin

2000

Tandem Reaction Sequences
Christopher Borths
Enantioselective Organic Catalysis
Jake Wiener
Asymmetric Photochemistry
Tehshik P. Yoon
Polymer Bound Catalysis
Vy Maria Dong
Enantioselective Carbonyl-Ene Reaction
Nick A. Paras
Lanthanides in Organic Chemistry
Tristan Lambert
Intramolecular Diels-Alder
Rebecca Wilson
Olefin Metathesis
Wendy S. Jen

Lectures

Enantioselective Organocatalysis Lecture 4
David MacMillan
Enantioselective Organocatalysis Lecture 3
David MacMillan
Enantioselective Organocatalysis Lecture 2
David MacMillan
Enantioselective Organocatalysis Lecture 1
David MacMillan